Conclusion Our study demonstrated that in patients with T2DM and obesity, semaglutide had a significant effect on weight loss and resulted in a more pronounced reduction in HbA1c compared with liraglutide
Energy metabolism of the normal heart Under normal physiological conditions, the heart generates adenosine triphosphate (ATP) through mitochondrial oxidative phosphorylation, utilizing fatty acids oxidation (FAO), glucose, lactic acid, ketone bodies, and amino acids (AA) (34, 35)
Most patients switching to tirzepatide start at the standard 2.5 mg weekly dose, regardless of their prior semaglutide dose
doi: 10.1016/j.bbadis.2017.05.007 141 BerglundEDViannaCRDonatoJKimMHChuangJ-CLeeCEet al
Hence, we can only speculate that differences in initial BMI and change in BMI following pharmacotherapy would have driven greater weight loss in those patients with SG